Effect of High-Dose Selenium on Postoperative Organ Dysfunction and Mortality in Cardiac Surgery Patients: The SUSTAIN CSX Randomized Clinical Trial.
JAMA Surg. 2023
Overview of oxidative stress and the role of micronutrients in critical illness.
JPEN J Parenter Enteral Nutr. 2022
Case presentation and panel discussion: Micronutrient therapy in critical illness.
JPEN J Parenter Enteral Nutr. 2022
Nutrition therapy in the older critically ill patients: A scoping review.
Lee ZY, Loh CTI, Lew CCH, Ke L, Heyland DK, Hasan MS
Ann Acad Med Singap. 2022
CHEST 2022
A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries
NEJM Video
Administration of vitamin D and its metabolites in critically ill adult patients: an updated systematic review with meta-analysis of randomized controlled trials
Critical Appraisal of a Systematic Review: A Concise Review
Early versus delayed enteral nutrition in mechanically ventilated patients with circulatory shock: a nested cohort analysis of an international multicenter, pragmatic clinical trial
IV Vitamin C in Critically Ill Patients A Systematic Review and Meta-Analysis
The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials
Validation of the modified NUTrition Risk Score (mNUTRIC) in mechanically ventilated, severe burn patients: A prospective multinational cohort study
A combination of enteral and parenteral nutrition in the acute phase of critical illness: An updated systematic review and meta-analysis
JPEN 2021: Hill A, Heyland DK, Ortiz A, Laaf E, Wendt S, Elke G, Stoppe C,
Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database
Association between ultrasound quadriceps muscle status with premorbid functional status and 60-day mortality in mechanically ventilated critically ill patients
Meeting Nutritional Targets of Critically Ill Patients by Combined Enteral and Parenteral Nutrition: Review and Rationale for the EFFORTcombo trial
NUTRIC-S proposal: Using SAPS 3 for mortality prediction in nutritional risk ICU patients
Nutritional therapy among burn injured patients in the critical care setting: An international multicenter observational study on best achievable practices
Clin Nutr 2020: Chourdakis M, Bouras E, Shields BA, Stoppe C, Rousseau AF, Heyland DK
Impact of Enteral Feeding on Vasoactive Support in Septic Shock: A Retrospective Observational Study
Nutr Clin Pract 2020: Matthew E, Aqeel M, Kozeniecki M, Patel K, Banerjee A,Heyland DK, Patel JJ
Safety and Outcomes of Early Enteral Nutrition in Circulatory Shock
JPEN 2020: Patel JJ, Rice T, Heyland DK.
Automated body composition analysis of clinically acquired computed tomography scans using neural networks
Clin Nutr 2020 (In Press: Paris MT, Tandon P, Heyland DK, Furberg H, Premji T, Low G, Mourtzakis M
Pharmacokinetics of omega-3 fatty acids in patients with severe sepsis compared with healthy volunteers: A prospective cohort study
Promotion of Regular Oesophageal Motility to Prevent Regurgitation and Enhance Nutrition Intake in Long-Stay ICU Patients. A Multicenter, Phase II, Sham-Controlled, Randomized Trial: The PROPEL Study
PEP uP (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol) in Surgical Patients-A Multicenter Pilot Randomized Controlled Trial
Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial
Are all low-NUTRIC-score patients the same? Analysis of a multi-center observational study to determine the relationship between nutrition intake and outcome
Clin Nutr 2019: Chourdakis M, Grammatikopoulou MG, Day AG, Bouras E, Heyland DK
The relevance of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentration for postoperative infections and postoperative organ dysfunctions in cardiac surgery patients: The eVIDenCe study
Vitamin D Supplementation in Mechanically Ventilated Patients in the Medical Intensive Care Unit
Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis. Nutrients
Phase 3 Pilot Randomized Controlled Trial Comparing Early Trophic Enteral Nutrition With No Enteral Nutrition in Mechanically Ventilated Patients With Septic Shock
Do We Have Clinical Equipoise (or Uncertainty) About How Much Protein to Provide to Critically Ill Patients?
Nutr Clin Pract (In press): Patel JJ, Rice T, Compher C, Heyland DK
Prediction of Prolonged ICU Stay in Cardiac Surgery Patients as a Useful Method to Identify Nutrition Risk in Cardiac Surgery Patients: A Post Hoc Analysis of a Prospective Observational Study
A multicenter, randomized, double-blind study of ulimorelin and metoclopramide in the treatment of critically ill patients with enteral feeding intolerance:PROMOTE trial
PEP uP (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol) in Surgical Patients: A Multicenter Pilot Randomized Controlled Trial
Greater Nutrient Intake Is Associated With Lower Mortality in Western and Eastern Critically Ill Patients With Low BMI: A Multicenter, Multinational Observational Study
JPEN 2018: Compher C, Chittams J, Sammarco T, Higashibeppu N, Higashiguchi T, Heyland DK.
Determination of Nutrition Risk and Status in Critically Ill Patients: What Are Our Considerations?.
Nutr Clin Pract 2018: Lee ZY, Heyland DK.
The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Registry-Based Randomized Trial: The EFFORT Trial.
Nutrition Adequacy Therapeutic Enhancement in the Critically Ill: A Randomized Double-Blind, Placebo-Controlled Trial of the Motilin Receptor Agonist Camicinal (GSK962040): The NUTRIATE Study
Improving Partnerships with Family members of ICU Patients study protocol for a randomized controlled trial
Intermittent versus Continuous Feeding in Critically ill Adults
Curr Opin Clin Nutr Metab Care 2018: Patel JJ, Rosenthal MD, Heyland DK
Should we Prescribe More Protein to Critically Ill Patients
Nutrients 2018: Heyland DK., Stapelton R., Compher C
Nutrition therapy in Australia and New Zealand Intensive Care Units: An international comparison study
JPEN 2018: Ridley EJ., Peake SL., Jarvis M., Lange K., Davies A.R., Chapman M
Nutrition support in Cardiac surgery patients - A narrative review
Greater Nutrient Intake is Associated with Lower Mortality in Western and Eastern Critically Ill Patients with low BMI: A Multicentre, Multinational Observational Study
JPEN 2018: Compher C, Chittams J, Sammarco T, Higashibeppu N, Higashibeppu T, Heyland DK
Vitamin C to Improve Organ Dysfunction in Cardiac Surgery Patients-Review and Pragmatic Approach
Vitamin D Supplementation in the Critically Ill: A Systematic Review and Meta-analysis
Clin Nutr 2017: Manzanares W, Langlois P, Szewc C, D’Aragon F, Heyland DK
A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial.
Greater Protein and Energy Intake May Be Associated With Improved Mortality in Higher Risk Critically Ill Patients: A Multicenter, Multinational Observational Study
Role of nutrition support in adult cardiac surgery: A consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery
A novel, family-centered intervention to improve nutrition in patients recovering from critical illness a feasibility study
Nutr Clin Pract 2017: Marshall A, Lemieux M, Dhaliwal R, Seyler H, MacEachern K, Heyland DK
Identifying nutritional risk in critical illness
Current Pulmonology Reports 2017: Kozeniecki M., Codner P., Heyland DK
High –dose intravenous selenium does not improve clinical outcomes in the cirtically ill;a systematic review and meta-analysis
Crit Care 2016: Manzanares W, Lemieux M, Elke G, Langlois PL, Bloos F, Heyland DK
Translation and adaptation of the NUTRIC Score to identify critically ill patients who benefit the most from nutrition therapy
Clinical Nutrition ESPEN 2016: Rosa M, Heyland DK, Fernandes D, Rabito EI, Oliveira ML, Marcadenti A
Nutritional risk assessment and cultural validation of the modified NUTRIC score in critically ill patients-A multicenter prospective cohort study
Nutrition Therapy in Critically Ill Patients Following Cardiac Surgery: Defining and Improving Practice
JPEN 2016: Rahman A, Agarwala R, Martin C, Nagpal D, Teitelbaum M, Heyland DK
Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial
Evaluation of Bioelectrical Impedance Analysis in Critically Ill Patients: Results of a Multicenter Prospective Study
Nutrition support practices in critically ill head-injured patients: a global perspective
Crit Care 2016: Chapple LA, Chapman MJ, Lange K, Deane AM, Heyland DK
Enhanced Protein-Energy Provision via the Enteral Route Feeding (PEPuP) protocol in critically ill surgical patients: a multicentre prospective evaluation
Anaesth Intensive Care 2016: Declercq B, Deane AM, Wang M, Chapman MJ, Heyland DK
What Is 'Best Achievable' Practice in Implementing the Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol in Intensive Care Units in the United States? Results of a Multicenter, Quality Improvement Collaborative
Existing equations to estimate lean body mass are not accurate in the critically ill: Results of a multicenter observational study
Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials
Validation of Bedside Ultrasound of Muscle Layer Thickness of the Quadriceps in the Critically Ill Patient (VALIDUM Study): A Prospective Multicenter Study.
Still a Place for Metoclopramide as a Prokinetic Drug in Critically Ill Patients?
JPEN 2015: van Zanten AR, van der Meer YG, Venhuizen WA, Heyland DK
Consequences of the REDOXS and METAPLUS Trials: The End of an Era of Glutamine and Antioxidant Supplementation for Critically Ill Patients?
JPEN 2015: van Zanten AR, Hofman Z, Heyland DK
Gastric residual volume in critically ill patients: a dead marker or still alive?
Nutr Clin Pract 2015: Elke G, Felbinger TW, Heyland DK
Identifying critically-ill patients who will benefit most from nutritional therapy: Further validation of the "modified NUTRIC" nutritional risk assessment tool
Clin Nutr 2015: Rahman A, Hasan RM, Agarwala R, Martin C, Day AG, Heyland DK
The Association between Nutritional Adequacy and Long-Term Outcomes in Critically Ill Patients Requiring Prolonged Mechanical Ventilation: A Multicenter Cohort Study
Crit Care Med 2015: Wei X, Day A, Ouellette-Kuntz H, Heyland DK
Clinical Outcomes Related to Protein Delivery in a Critically Ill Population: A Multicenter, Multinational Observation Study.
JPEN 2015: Nicolo M, Heyland DK, Chittams J, Sammarco T, Compher C
Fish Oil-Containing Emulsions: When Fat Seems to Improve Clinical Outcomes in the Critically Ill.
JPEN 2015: Manzanares W, Langlois PL, Lemieux M, Heyland DK
Safety of Prolonged Use of Trophic Feeds in the Critically Ill Patient: It Depends on the Nutrition Risk of the Patient!
Adequate enteral protein intake is inversely associated with 60-d mortality in critically ill children: a multicenter, prospective, cohort study
Am J Clin Nutr 2015: Mehta NM, Bechard LJ, Zurakowski D, Duggan CP, Heyland DK
Metabolic and nutritional support of critically ill patients: consensus and controversies
Intravenous fish oil lipid emulsions in critically ill patients: an updated systematic review and meta-analysis
Crit Care 2015: Manzanares W, Langlois PL, Dhaliwal R, Lemieux M, Heyland DK
Should We PERMIT Systematic Underfeeding in All Intensive Care Unit Patients? Integrating the Results of the PERMIT Study in Our Clinical Practice Guidelines
Revised Questionnaire to Assess Barriers to Adequate Nutrition in the Critically ill.
JPEN 2015: Cahill NE, Jiang X, Heyland DK.
Combining nutrition and exercise to optimize survival and recovery from critical illness: Conceptual and methodological issues.
Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis.
Crit Care 2015: van Zanten AR, Dhaliwal R, Garrel D, Heyland DK
A multi-faceted, family-centred nutrition intervention to optimise nutrition intake of critically ill patients: The OPTICS feasibility study.
Aust Crit Care 2015: Marshall AP, Wake E, Weisbrodt L, Dhaliwal R, Spencer A, Heyland DK
Enhanced Protein-Energy Provision via the Enteral Route in Critically Ill Patients (PEP uP Protocol): A Review of Evidence
Nutr Clin Pract 2015: Lee ZY, Barakatun-Nisak MY, Airini IN, Heyland DK
Enternal Nutrition in Critically III Septic Patients - Less or More?
Pharmaconutrition With Selenium in Critically Ill Patients: What Do We Know?
Nutrition in Clinical Practice 2015 : Manzanares W, Langlois PL, Heyland DK
Nutrition therapy for the critically ill surgical patient with aortic aneurismal rupture: defining and improving current practice.
JPEN 2015: Rahman A, Martin C, Heyland DK
Clinical Outcomes in Critically Ill Patients Associated With the Use of Complex vs Weight-Only Predictive Energy Equations
JPEN 2015: Compher C, Nicolo M, Chittams J, Kang Y, Day AG, Heyland DK
Gastric vs Small Bowel Feeding in Critically Ill Neurologically Injured Patients: Results of a Multicenter Observational Study
JPEN 2015: Saran D, Brody RA, Stankorb SM, Parrott SJ, Heyland DK
The prevalence of iatrogenic underfeeding in the nutritionally 'at-risk' critically ill patient: Results of an international, multicenter, prospective study
Clin Nutr 2015: Heyland DK, Dhaliwal R, Wang M, Day AG
Implementing the PEP uP Protocol in Critical Care Units in Canada: Results of a Multicenter, Quality Improvement Study
JPEN 2015: Heyland DK, Dhaliwal R, Lemieux M, Wang M, Day AG
International observational study of nutritional support in mechanically ventilated patients following burn injury
Burns 2015: Czapran A, Headdon W, Deane AM, Lange K, Chapman MJ, Heyland DK
Prevalence, risk factors, clinical consequences, and treatment of enteral feed intolerance during critical illness
Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial
Evaluation of nutrition deficits in adult and elderly trauma patients
JPEN 2015: Wade CE, Kozar RA, Dyer CB, Bulger EM, Mourtzakis M, Heyland DK
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