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Critical Care Nutrition at the Clinical Evaluation Research Unit (CERU)

is dedicated to improving nutrition therapies in the critically ill through knowledge generation, synthesis, and translation. We engage in a broad range of research activities and promote a culture of best practices in critical care nutrition. Ultimately, this will result in improved clinical outcomes for critically ill patients and increased efficiencies to our health care systems.

The Effect of High Protein Dosing in Critically Ill Patients:

A Multicenter Registry-based Randomized Trial

The EFFORT Trial

Synopsis: In this project, we aim to combine the International Nutrition Survey (INS) with the power of randomization to conduct a registry-based randomized clinical trial (RRCT). The specific purpose of the current proposal is to provide the rationale for a large clinical trial of 2 different protein doses that demonstrate the value of extra protein supplementation in critically ill, nutritionally high-risk patients using the INS as a type of RRCT.


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EFFORT is open for registration! Interested ICUs should proceed to obtain local site and ethics approvals. Instructions and other support materials for these activities can be downloaded by clicking on the "Get Started" button below.

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